Comparative mutant prevention concentration and mutant selection window of sitafloxacin versus other quinolones using strains of Haemophilus influenzae with decreasing susceptibility to levofloxacin.

نویسندگان

  • Shigeki Nakamura
  • Katsunori Yanagihara
  • Yoshitomo Morinaga
  • Koichi Izumikawa
  • Masafumi Seki
  • Hiroshi Kakeya
  • Yoshihiro Yamamoto
  • Shimeru Kamihira
  • Shigeru Kohno
چکیده

Title Comparative mutant prevention concentration and mutant selection window of sitafloxacin versus other quinolones using strains of Haemophilus influenzae with decreasing susceptibility to levofloxacin. Author(s) Nakamura, Shigeki; Yanagihara, Katsunori; Morinaga, Yoshitomo; Izumikawa, Koichi; Seki, Masafumi; Kakeya, Hiroshi; Yamamoto, Yoshihiro; Kamihira, Shimeru; Kohno, Shigeru Citation International Journal of Antimicrobial Agents, 33 (5), pp.489-490; 2009

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Rapid bactericidal activity of sitafloxacin against Streptococcus pneumoniae.

The initial bactericidal activity of quinolones against Streptococcus pneumoniae at the concentration equivalent to their respective peak serum concentration (C(max)) and free drug fraction of C(max) (fC(max)) were investigated. The bactericidal activity of sitafloxacin (STFX), levofloxacin (LVFX), moxifloxacin (MFLX), and garenoxacin (GRNX) were compared by determining the actual killing of ba...

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عنوان ژورنال:
  • International journal of antimicrobial agents

دوره 33 5  شماره 

صفحات  -

تاریخ انتشار 2009